Medical physics 

Medical Physics group published 17 per review papers and two PhD theses (Touko Kaasalainen and Juha Koivisto) were conducted in 2015. The research is being conducted in by a large group of dedicated researchers consisting of important collaborators from Helsinki University Hospital and STUK. Research is focused in the development of novel methods and applications for medical imaging and therapy.  Medical physics researchers had presentations in the main international congresses in the field including RSNA (Chicago), ECR (Vienna), MICCAI (Munich), ESMRMB (Edinburgh) and EANM (Hamburg). In the national meetings the main activity was in “Physics Days” in Helsinki and “Sädeturvapäivät” in Tampere. In clinical routine work, the biggest single effort was given to clinical audits that were performed in different units of HUH.

Scientific research was performed on CT optimization, cardiac MR (CMR) imaging and digital breast tomosynthesis (DBT).  CMR research focused on utilizing T1-mapping in diagnosing cardiac diseases.  The ongoing research also contains studies about DBT where different imaging systems are compared on technical image quality.

The research in clinical neurophysiology has focused on developing electrophysiological recordings of babies and children, and on recording normal values for motor and visual evoked potentials. 

In the field of ultrasound imaging the write off reason of ultrasound transducers was studied in depth. The purpose of the review was to streamline the whole ultrasound quality assurance process by concentrating on the parameters which have the most sensitivity on the transducer performance.

The work on medical image processing has focused on developing and providing advanced computational methods and automated tools for imaging based research, clinical applications and quality control. Other activities include development of methods for cell segmentation from 3D microscopy data and 3D printing.  

In new promising radiotherapies like radionuclide therapies biological effects of the radiation have to be studied on cellular scale. The aim of the research is to develop more realistic 3D cell cluster models and dosimeter software for the cellular and sub-cellular dosimeter and to study the significance of the models for the analysis of the biological effects of the radiation. State-of-the-art 3D microscope technology is used to generate the necessary data for the models. 177Lu post-therapy activity distribution can be imaged using a calibrated SPECT/CT system and physically accurate dose distribution can be simulated from the images using Monte Carlo (MC) simulations. Simulating electron dose using MC is time consuming and is not typically feasible in clinical practice.